My TV is VIZIO E420-B1
I have tested it with the Nintendo Wii and Sega Saturn
Both work really well. 5x scale seems to cut out some of the picture and it’s not as full as I’ve seen on other TV’s, but the other scalers work well and the picture is really crisp. I have not tested this with other consoles like genesis or SNES, but I do want to expand my collection and I’ll update if I find any incompatibilities.