Yes I would absolutely recommend you lift up pin 50, that is what made mine look perfect from being a mess before.
If you still have issues after this maybe look at snipping the legs on the CXA1145 (20/21/22/10).
Good luck! it really is worth it, I have been playing my Megadrive constantly since I got this working, especially good with the OSSC and turning on scanlines = )
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